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PPD

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (1) Endogenous Metabolite (1) HMG-CoA Reductase (HMGCR) (2) Isotope-Labeled Compounds (2) Phosphatase (1)
By Research Areas:	Cardiovascular Disease (3) Metabolic Disease (2) Neurological Disease (1)

8

Inhibitors & Agonists

1

Biochemical Assay Reagents

3

Natural
Products

2

Recombinant Proteins

2

Isotope-Labeled Compounds

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15906

AMPPD

Lumi-Phos Plus; Lumigen PPD; PPD
Phosphatase Others

AMPPD, a 1,2-dioxo-cyclohexane derivative, is a biochemistry ultrasensitive alkaline phosphatase substrate.

Bemfivastatin PPD 10558	HMG-CoA Reductase (HMGCR)	Cardiovascular Disease Metabolic Disease
Bemfivastatin (PPD 10558) is an orally active, HMG-CoA Reductase (HMGCR) inhibitor, also known as Statin. Bemfivastatin enhances the activity of liver extraction. Bemfivastatin exhibits little developmental toxicity effects in pregnant rats and rabbits via daily oral doses during organogenesis period. The no observed adverse effect level (NOAEL) are ≥320 mg/kg/day for rats developmental toxicity, 12.5 mg/kg/day for rabbits maternal toxicity, and 25 mg/kg/day for rabbits developmental toxicity, respectively. Bemfivastatin can be used for research on Statin-related hypercholesterolemic myalgia with inability to tolerate statins .

Bemfivastatin hemicalcium PPD 10558 hemicalcium	HMG-CoA Reductase (HMGCR)	Cardiovascular Disease Metabolic Disease
Bemfivastatin (PPD 10558) hemicalcium is an orally active lipid-lowering agent and HMG-CoA reductase inhibitor. Bemfivastatin hemicalcium enhances the activity of liver extracts. Bemfivastatin hemicalcium has no-observed adverse effect levels (NOAEL) with dosages of ≥320 mg/kg/d (rat developmental toxicity), ≥12.5 mg/kg/d (rabbit maternal toxicity), ≥25 mg/kg/d (rabbit developmental toxicity), respectively. Bemfivastatin hemicalcium can be used in the study of statin-related hypercholesterolemic myalgia in statin-intolerant patients.

HY-153169

6PPD-Q

6PPD-Quinone
Endogenous Metabolite Others

6PPD-Q (6PPD-Quinone) is an endogenous metabolite that can be found in human urine and can also commonly found in the environment .
HY-152039S

6PPD-quinone-d5

Isotope-Labeled Compounds Others

6PPD-quinone-d₅ is the deuterium labeled 6PPD-quinone[1].
HY-152039S1

6PPD-quinone-13C6

Isotope-Labeled Compounds Others

6PPD-quinone- ¹³C₆ is the ¹³C labeled 6PPD-quinone[1].

Notoginsenoside Fa	Others	Neurological Disease
Notoginsenoside Fa, a protopanaxadiol (ppd)-type saponin isolated from P. notoginseng, could possibly activate and recover the function of degenerated brain .

Notoginsenoside Fc	Autophagy	Cardiovascular Disease
Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy .

Cat. No.	Product Name	Category	Target	Chemical Structure

6PPD-Q 6PPD-Quinone	Quinones Structural Classification Alkaloids Other Alkaloids Benzene Quinones	Endogenous Metabolite
6PPD-Q (6PPD-Quinone) is an endogenous metabolite that can be found in human urine and can also commonly found in the environment .

Notoginsenoside Fa	Triterpenes Terpenoids Source classification Plants Panax notoginseng Araliaceae	Others
Notoginsenoside Fa, a protopanaxadiol (ppd)-type saponin isolated from P. notoginseng, could possibly activate and recover the function of degenerated brain .

Notoginsenoside Fc	Cardiovascular Disease Triterpenes Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Panax notoginseng Araliaceae	Autophagy
Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy .

Species:	Human (2)
Tag:	His (2)
Source:	Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

	AGO2/Argonaute-2 Protein, Human (sf9, His) Protein argonaute-2; hAgo2; eIF-2C 2; PPD; AGO2; EIF2C2	Human	Sf9 insect cells
	The AGO2/Argonaute-2 protein is critical for RNA-mediated silencing complex (RISC)-mediated gene silencing. In "minimal RISC," AGO2 binds to short guide RNAs, such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), to guide RISC for silencing with complementary mRNAs. AGO2/Argonaute-2 Protein, Human (sf9, His) is the recombinant human-derived AGO2/Argonaute-2 protein, expressed by Sf9 insect cells , with N-His, N-10*His labeled tag. The total length of AGO2/Argonaute-2 Protein, Human (sf9, His) is 859 a.a., with molecular weight of ~99 kDa.

	HPD/HPPDase Protein, Human (His) rHu4-hydroxyphenylpyruvate dioxygenase /HPD, His; 4-Hydroxyphenylpyruvate Dioxygenase; 4-Hydroxyphenylpyruvic Acid Oxidase; 4HPPD; HPD; HPPDase; HPD; PPD	Human	E. coli
	HPD is a key enzyme in tyrosine catabolism and plays a key role in catalyzing the conversion of 4-hydroxyphenylpyruvate into homogentisate. This enzymatic process represents a key step in the tyrosine metabolic pathway and contributes to the breakdown of this amino acid. HPD/HPPDase Protein, Human (His) is the recombinant human-derived HPD/HPPDase protein, expressed by E. coli , with N-6*His labeled tag. The total length of HPD/HPPDase Protein, Human (His) is 393 a.a., with molecular weight of 40-50 kDa.

Cat. No.	Product Name	Chemical Structure

HY-152039S1

6PPD-quinone-13C6

6PPD-quinone- ¹³C₆ is the ¹³C labeled 6PPD-quinone[1].
HY-152039S

6PPD-quinone-d5

6PPD-quinone-d₅ is the deuterium labeled 6PPD-quinone[1].

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